AO Foundation

Short Description The AO Research Institute in Davos is seeking an enthusiastic early-stage researcher for an internship in our Field-Assisted Biofabrication (FAB) Lab. The position offers an opportunity to contribute to innovative research in biofabrication and bioassembly, focusing on the application of extrinsic fields (hydrodynamic waves, magnetic fields, light) and stimuli-responsive materials for tissue modelling and regeneration. Main Responsibilities Assist in the development and optimization of biofabrication technologies using hydrodynamic waves, magnetic fields, and light-based methods. Support experiments involving stimuli-responsive materials for tissue regeneration and organoid modelling. Contribute to cell culturing, imaging, and data analysis. Collaborate with lab members on ongoing research projects and prepare results for publication. Main Requirements MSc in Biofabrication, Material Science, Biomedical Engineering, Biology, Biotechnology, Biophysics, or a related field (or currently enrolled in an MSc program). Experience with 3D printing, hydrogels, biomaterials, cell culture, organoid generation, and imaging techniques is highly desirable. Familiarity with data analysis tools (e.g., microscopy, statistical software) is an advantage. Strong interest in biofabrication, tissue engineering, and regenerative medicine. Ability to work both independently and collaboratively in a research setting.

Short Description Fracture-related infection (FRI) remains one of the most challenging complications in orthopedic and musculoskeletal trauma surgery. The Infection Biology team at ARI performs basic and translational studies that aim to provide a better understanding of the pathology of FRI, and develop improved interventional strategies to prevent and/or treat FRI. We are looking for a highly motivated postdoctoral research associate to join the Infection Biology Focus Area of the AO Research Institute Davos (ARI). Main Responsibilities The successful applicant will be working within a multi-disciplinary team investigating developing and testing novel antibacterial interventions for the treatment of Staphylococcus aureus bone infection. The position may be particularly suitable for candidates experienced in microbiology (biofilm and/or phage biology) with an interest in developing cross disciplinary skills including molecular biology (recombinant protein production), biomaterials science and preclinical in vivo testing. The successful applicant will join ongoing studies at ARI. A major focus will be further development of antibiofilm technology utilizing self-healing biomaterials and enzyme-based antimicrobials. This will involve biofilm culture and eradication assessment (culture-based and microscopy) as well as recombinant protein production according to preexisting protocols. In addition, the job holder will contribute to the preclinical in vitro and in vivo evaluation of bacteriophage-based implant coatings in conjunction with external collaborators. Main Requirements The ideal candidate is an independent thinker, highly self-motivated and holds a PhD degree in microbiology, biomedical engineering, or a related field and has excellent all-around bacteriology laboratory skills. Experience in mammalian cell culture, confocal microscopy and biomaterials (hydrogels) will be valued, but not required. Familiarity with a cross-cultural/interdisciplinary environment is an advantage. Eligibility to apply and obtain a Visa for temporary residence is Switzerland is essential. We require good English language skills, a work ethic suitable to the challenges we plan to offer. Familiarity with a cross-cultural/interdisciplinary environment is an advantage. The position is based in Davos for an initial period of 2 years, with ideal starting date Spring /Summer 2025.

Short Description We are seeking an experienced international Project Manager to manage the AO Milestones program delivery, ensuring timely delivery across multiple workstreams. Working closely with the AO Milestones Program Owner and an international project team, the Project Manager will drive operational excellence, manage diverse stakeholders, and establish project management standards and build capabilities across the AO Education Institute. The role requires expertise in project management methodologies (such as Scrum, Agile, Kanban) with a preference for candidates experienced in the educational sector. Main Responsibilities Together with the Product owner, develop project management processes that support product development and efficient life cycle management with focus on innovation, business value and quality. Support the product owner in developing and implementing project management framework to be scalable across the organization. Oversee the successful delivery of the AO Milestones project goals, managing complex workstreams with diverse global stakeholders. Lead cross-functional (curriculum design, platform development and implementation) to ensure project success. Drive strategic project goals and process improvements to enhance AO Milestones' competitiveness in the global medical education market. Ensure the integration of human-centered design principles into all program phases. Introduce agile project management, visual project management, and other effective project management methods. Accountable to Manage project timelines, risks, and resources to deliver high-quality outcomes. Build and maintain strong relationships with internal and external stakeholders, ensuring clear communication and alignment. Monitor program KPIs to ensure performance aligns with business and educational objectives. Main Requirements Bachelor’s degree in project management, education, or a related field. Project management education, PMP or similar certifications, and training in change management preferred. Proven track record in international project management, preferably in the educational sector or medical devices. Strong preference for an independent, proactive, and goal-oriented work approach to apply expertise and foster collaboration in achieving fast-paced goals in line with management expectations and project timelines. Extensive experience managing cross-functional teams in matrix organizations. Strong expertise in Scrum and Agile methodologies. Focus on targets and results, showing a high level of endurance, tolerance, and resilience. Advanced stakeholder management skills. Strategic and operational mindset with the ability to balance competing priorities. Strong understanding of human-centered design principles and their application in educational projects. Ability to navigate and manage complex stakeholder landscapes Proficiency in English This is a temporary role, until 31.12.2026

Main Responsibilities Conducting all tasks regarding clinical data management with AO ITC, such as: Set up and validation of clinical study databases in the field of trauma and orthopedics Set up, implement and oversee Data Management Plans and Data Validation Plans Support and supervision of data cleaning and data clarification activities Data base user management for clinical research projects Management and maintenance of the AO ITC case report form template library Maintenance and further development of Clinical Data Management SOPs Line management optional In General: Functional lead of the Clinical Data Management team, including resource planning, cross-functional communication and leading the Data Management Jam Sessions Supporting the Head of Clinical Operations in strategical decisions related to the Clinical Data Management team (e.g., development of budgets, project prioritization, further education goals) Main Requirements Education: Degree in Information Technology, Computer Science, Life Sciences, or related field. Equivalent education or certification in clinical data management or database development will also be considered. Basic level of medical knowledge of advantage Job Specification: Extensive experience with data management in clinical research, particularly in utilizing electronic data capture (EDC) systems such as REDCap Academic, REDCap Cloud, and Medidata Experience in managing the full data lifecycle from data collection to final reporting, ensuring accuracy, completeness, and consistency. Ability to develop and maintain databases, including designing and implementing case report forms, queries, and reports. Able to lead the configuration, design, and administration of REDCap and Medidata platforms for clinical trials or research projects. Experienced in implementing study-specific case report forms, including programming automated data validation rules and range checks. Used to designing, implementing, and monitoring data validation protocols to ensure data integrity and regulatory compliance. Able to conduct thorough data quality checks, consistency checks, and identify discrepancies between data sources. Familiarity with data privacy regulations and guidelines, such as GDPR and HIPAA, in the context of clinical data handling Proficient knowledge of MS Office work package, especially MS Excel, project management software (e.g., MS Project, JIRA) and clinical data management tools Expertise in designing, setting up, and managing clinical databases adhering to global clinical data standards, such as CDISC, including CDASH and SDTM standards Demonstrated ability to manage complex clinical data management workflows with strong organizational, planning, and follow-up capabilities Attention to detail and reliability Collaborative and team-oriented with the ability to work cross-functionally Flexibility and customer-oriented mindset Strong written and oral communication in English, German skills are of advantage